✅ Product Benefits
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Potent fungicidal action: Terbinafine inhibits squalene epoxidase, disrupting fungal cell membrane formation and effectively clearing dermatophyte infections including Trichophyton rubrum and T. mentagrophytes. turn0search1turn0search2
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Wide clinical indications: Effective for skin conditions like tinea corporis, cruris, pedis, and fungal nail infections (onychomycosis). Also available in topical cream, spray, and granule forms for scalp infections. turn0search1turn0search6
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Once‑daily regimen enhances adherence: Adults take 250 mg once daily. Typical durations vary: 6 weeks for fingernail infections and 12 weeks for toenail infections; 1–6 weeks for skin infections. turn0search1turn0search2
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Locally accessible & budget-friendly: Priced at approximately ৳ 50 per tablet (~৳ 500 for 10‑tablet strip). Widely available across Bangladesh pharmacies and online platforms. turn0search2turn0search12
ℹ️ Dosage Guide & Administration
| Condition | Adult Dose | Duration |
|---|---|---|
| Onychomycosis (fingernails) | 250 mg once daily | ~6 weeks |
| Onychomycosis (toenails) | 250 mg once daily | ~12 weeks |
| Tinea corporis/cruris | 250 mg once daily | 2–4 weeks |
| Tinea pedis (athlete’s foot) | 250 mg once daily | ~1 week |
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Child dosage (≥4 years, <25 kg): 125 mg daily; higher weight groups adjust accordingly. Terbinafine may be taken with or without food. turn0search1turn0search3
⚠️ Safety & Precaution Notes
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Common side effects: Include gastrointestinal upset (nausea, diarrhea), headache, taste disturbance, rash, muscle/joint pain, fatigue, dizziness, and rarely tingling neuropathy. turn0search2turn0search6
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Liver toxicity risk: Rare but serious hepatotoxic reactions reported. LFTs should be checked in prolonged treatment; therapy discontinued if elevated transaminases occur. Avoid in active liver disease. turn0search9turn0search3
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Drug interactions: Terbinafine inhibits CYP2D6—may elevate levels of drugs like tricyclic antidepressants, SSRIs, beta-blockers, and certain antiarrhythmics. Alcohol should be avoided. turn0search13turn0search9
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Use in pregnancy/lactation: Safety during pregnancy is uncertain; use only if benefits justify risks. Passes into breastmilk—avoid during breastfeeding. turn0search2turn0search4
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Overdose: Up to 5 g ingested without serious effects. Potential symptoms: nausea, vomiting, abdominal pain, dizziness, rash, headache, frequent urination. Supportive care advised. turn0search14turn0search0
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Baseline liver monitoring recommended, especially for those with prior hepatic conditions or extended therapy durations. turn0search3turn0search9
✅ Quick Summary Table
| Feature | Details |
|---|---|
| Active Ingredient | Terbinafine Hydrochloride 250 mg |
| Therapeutic Class | Allylamine antifungal |
| Indications | Tinea infections (skin, nails) |
| Typical Dose | 250 mg once daily |
| Common ADRs | GI disturbance, headache, rash, taste changes |
| Serious Risks | Rare hepatotoxicity, hypersensitivity reactions |
| Price in BD | ~৳ 50 per capsule; ~৳ 500 per strip |
| Manufacturer | UniMed UniHealth Pharmaceuticals Ltd. |
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