✅ Product Benefits

1. Combined antihypertensive efficacy
   Offers additive blood pressure-lowering by combining a cardioselective beta-blocker (Bisoprolol) with a low-dose thiazide diuretic (Hydrochlorothiazide).

2. Low-dose diuretic to reduce electrolyte imbalance
   Hydrochlorothiazide 6.25 mg enhances antihypertensive effect with lower hypokalemia risk versus higher-dose thiazides. 

3. Once-daily dosing for convenience
   Commences at 2.5 mg/6.25 mg once daily; can be titrated up every 14 days as needed to 20 mg/12.5 mg once daily. 

4. Suitable replacement therapy
   Patients stabilized on individual agents at the same doses may be transitioned to this fixed‑dose combination for ease of use. 

5. Well-tolerated safety profile
   Common side effects include fatigue, dizziness, headache, bradycardia, orthostatic hypotension, cold extremities, gastrointestinal discomfort; generally mild and transient. Contraindicated in cardiogenic shock, severe bradycardia, AV block, or sulfonamide allergy. 

6. Meets heart failure and angina indications
   Useful in essential hypertension, chronic stable angina, and heart failure management alongside other required therapies

7. Affordable and accessible in Bangladesh
   Priced around ৳6.02 per tablet (৳60.20 per strip of 10) and widely available across pharmacies