✅ Product Overview

• Product Name: Amaryl 1 mg Tablet

• Generic Name: Glimepiride

• Manufacturer: Sanofi (in Bangladesh marketed by Sanofi Bangladesh / Synovia Pharma) 

• Type: Sulfonylurea antidiabetic agent

• Form: Oral Tablet, 1 mg strength

📦 Product Description

Amaryl 1 mg Tablet (Glimepiride) is prescribed as an adjunct to diet and exercise for managing type 2 diabetes mellitus when blood glucose control is inadequate. It stimulates insulin release from pancreatic beta cells, lowers hepatic glucose production, and improves peripheral insulin sensitivity to help maintain healthy blood sugar levels for up to 24 hours. 

🌟 Product Benefits & Features

1. Effective blood glucose control when diet and exercise alone are insufficient in type 2 diabetes mellitus 

2. Once‑daily dosing with full effect lasting ~24 hours for convenient glycemic control 

3. Flexible titration:

   • Initial adult dose: 1 mg once daily (especially in elderly or renal-impaired patients)

   • Maintenance dose: 1–4 mg/day

   • Maximum: 8 mg/day, adjusted in 1–2 mg increments at 1–2-week intervals based on response 

4. Affordable locally: Approx ৳ 0.46 per tablet; ৳ 6.90–6.92 per tablet in retail packs (~৳ 103–415 per pack) in Bangladesh 

5. Can be combined with metformin or insulin when needed—but this increases risk of hypoglycemia requiring close monitoring 

6. Known side effect profile: typically well tolerated, but watch for hypoglycemia, nausea, headache, dizziness, weight gain 

⚠️ Important Safety & Usage Considerations

• Hypoglycemia risk: Most concerning side effect. Symptoms include sweating, dizziness, shakiness, confusion, hunger, fast heartbeat. Keep quick sugar sources readily available. 

• Take with breakfast or with the day’s first main meal to reduce hypoglycemia risk. 

• Use caution in elderly, and those with liver or kidney impairment; severe dysfunction is contraindicated. 

• Drug interactions: Avoid alcohol; be cautious with medications like ACE inhibitors, azole antifungals, certain antibiotics, beta-blockers (which may mask low sugar symptoms), rifampicin, corticosteroids, thyroid hormones, etc. 

• Contraindications: Not for type 1 diabetes, diabetic ketoacidosis, severe hepatic/renal disease, G6PD deficiency, pregnancy, or lactation